Jack Lee is a white lawyer from Freeman County, Virginia, who has never done anything to push back against racism, until he decides to represent Jerome Washington, a Black man charged with brutally killing an elderly and wealthy white couple. Doubting his decision, Lee fears that his legal skills may not be enough to prevail in a case where the odds are already stacked against both him and his client. Desiree DuBose is a Black lawyer from Chicago who has devoted her life to furthering the causes of justice and equality for everyone. She comes to Freeman County and enters a fractious and unwieldy partnership with Lee in a legal battle against the best prosecutor in the Commonwealth. Yet DuBose is also aware that powerful outside forces are at work to blunt the victories achieved by the Civil Rights era.