Florence, the 1550s. Lucrezia, third daughter of the grand duke, is comfortable with her obscure place in the palazzo: free to devote herself to her own artistic pursuits. But when her older sister dies on the eve of her wedding to the ruler of Ferrara, Modena and Reggio, Lucrezia is thrust into the limelight: the duke is quick to request her hand in marriage and her father just as quick to accept on her behalf. Having barely left girlhood behind, Lucrezia must now enter an unfamiliar court where her arrival is not universally welcomed. Perhaps most mystifying of all is her new husband himself, Alfonso. Is he the playful sophisticate he appeared to be before their wedding, or the ruthless politician before whom even his formidable sisters seem to tremble?