A bereaved doctor undertakes a diabolical experiment in a shattering philosophical thriller that anticipates the moral, social, and metaphysical dilemmas science is poised to confront. Davis Moore is a fertility doctor in Chicago specializing in reproductive cloning, a controversial and closely regulated new practice, when his seventeen-year-old daughter is brutally raped and murdered. The case is investigated but never solved. Months later, Moore retrieves her belongings from the police, and finds among them a vial containing the killer's DNA. Tormented by grief, Moore entertains a monstrous thought: the possibility of cloning not his daughter but the man who killed her. How far would you go to look into the face of your daughter's murderer?

Justin Finn, at three, looks like any other child. Bright, joyful, sweet; an innocent toddler to his unsuspecting parents and to all who know him. But his face, one day, will be the exact match of the cold-blooded killer of whom he is a perfect genetic replica. Can a three-year-old have a past? Where does evil come from?

What happens to the soul when we die? What are you duplicating when you duplicate a human life?

Cast of Shadows is a spectacularly original, hair-raising novel about the fate of a little boy brought into the world to solve a crime. Relentlessly gripping, profoundly unsettling, and visionary, it introduces a major new suspense novelist.